I switched over to using Chrome almost exclusively on MS Windows a few months ago with great satisfaction. For the past week or two, I've also been using Chrome on Linux and the Mac version. They are all working pretty well now. I'm now using Chrome nearly all of the time on all platforms.
It's important to note that neither the Mac or Linux versions have actually been released, so they are not in their final form and don't have that level of usability.
However, the Mac version seems to be extremely stable. It supports Flash (Youtube videos) and I haven't experienced any problems with it at all.
The Linux version is a little less stable and doesn't have Flash support yet. Still, using it through most of every day, I only load Firefox for the occasional video.